University College of Science, OU

Dr.M.Vasavi

Dr.M.Vasavi, M.Sc, Ph.D.

Assistant Professor,

Department of Chemistry, University College of Science, OU

Saifabad, Hyderabad - 500004

Contact Addresses

Residence
Phone (office)	91-040-23393530
Phone (residence, cell)
email	mvasavi@osmania.ac.in

Educational Qualifications

M.Sc, Ph.D.

Additional Qualifications

Experience

Teaching Areas

Bioinformatics and Drug Designing.

Seminars/Conferences/Workshops

Attended : 32
Papers Presented : 28
Organized : 4

Publications

Papers : 19 + Patents : 3
Books : Nil
Patents :
- Design, Synthesis and Cytotoxic Studies of Piperazine Derivatives against Cancer. Uma Vuruputuri, SaritaRajenderPotlapally, Vasavi Malkhed, Kiran Kumar Mustyala, RamasreeDulapalli, V.G.M. Naidu. Indian Patent application number 5681/CHE/ 2014 (Publication Date: 19/12/2014).
- Synthesis and Cytotoxic Studies of Barbituric Acid Derivatives. Uma Vuruputuri, SaritaRajenderPotlapally, BhargaviKondagari and Vasavi Malkhed, Indian Patent application number 3345/CHE/2012 (Publication Date: 07/03/2014).
- Novel Entities for Mycobacterium tuberculosis – Design, Synthesis and Activity. Uma Vuruputuri, Vasavi Malkhed, Kiran Kumar Mustyala, SaritaRajenderPotlapally, Ramasree Dulapalli, Srinand Sreevatsan, Anthony David Baughn. Indian Patent application number – 6190/ CHE/ 2014 (Publication Date: 26/08/2016).

Publications

Identification of small molecular inhibitors for efflux protein Rv2688c of Mycobacterium tuberculosis, Vadija R, Mustyala KK,Malkhed V, Dulapalli R, Veeravarapu H, Malikanti R, Vuruputuri U,2018, BiotechnolApplBiochem 608-621(Impact Factor 1.413).
Identification of small molecular ligands as potent inhibitors of fatty acid metabolism in Mycobacterium tuberculosis, Ramesh Malikanti, RajenderVadija, HymavathiVeeravarapu, Kiran Kumar Mustyala, Vasavi Malkhed , Uma Vuruputuri, 2017,Journal of Molecular Structure 1150, 227 – 241 (Impact Factor 1.75)
Development of an in vitro Bioassay for Recombinant Human Erythropoietin (rHuEPO) Based on Proliferative Stimulation of an Erythroid Cell Line and Analysis of Sialic Acid Dependent Microheterogeneity: UT-7 Cell Bioassay, MK Metta, V Malkhed, S Tantravahi, U Vuruputuri, R Kunaparaju, 2017, The Protein Journal, 36, 112-122(Impact Factor 1.139)
Design of novel lead molecules against RhoG protein as cancer target–a computational study, ThirupathiDasari, BhargaviKondagari, RamasreeDulapalli, Aboubakr Haredi Abdelmonsef, ThirupathiMukkera, LavanyaSoudaPadmarao, Vasavi Malkhed, Uma Vuruputuri, 2017, Journal of Biomolecular Structure and Dynamics, 35, 14, 3119-3139 (Impact Factor 3.12)
Identification of Small Molecular Inhibitors for Efflux Protein: DrrA of Mycobacterium tuberculosis, Kiran Kumar Mustyala, Vasavi Malkhed, VenkataRamana Reddy Chittireddy, Uma V.Cel. Mol. Bioeng. 2016, 9 (1), 190-202 (Impact Factor 2.535)
Virtual screening studies to identify novel inhibitors for Sigma F protein of Mycobacterium tuberculosis, Kiran, K. M.; Vasavi, M.; Venkataramana, R. Ch.; Uma, V. I. J. Myco. 2015, 4 (4), 330-336 (Impact Factor 0.53)
Macromolecular structure and interaction studies of SigF and Usfx in Mycobacterium tuberculosis. Kiran, K. M.; Vasavi, M.; Sarita, R. P.; Venkataramana Reddy, C.; Uma, V. J. Recept. Signal. Transduct. Res. 2014, 34, 3, 162-173. (Impact Factor 1.61)
Identification of novel leads applying in silico studies for Mycobacterium multidrug resistant (MMR) protein. Vasavi, M.; Kiran, K. M.; Sarita, R. P.; Uma, V. J. Biomol. Struct. Dyn. 2013, 32, 1889-1906.(Impact Factor 3.12)
A Molecular Dynamic Simulations of Co (III) and Ru (II) polypyridyl complexes and its docking studies with dsDNA. Navaneetha, N.; Nagababu, P.;, Kiran, K. M.; Vasavi, M.; Ramasree, D.; Satyanarayana,S.; Uma, V. Med. Chem. Res. 2013, 22, 5557-5565. (Impact Factor 1.27)
Modeling of alternate RNA polymerase sigma D factor and identification of novel inhibitors by virtual screening, Vasavi, M.; Kiran, K. M.; Sarita, R. P.; Uma, V.Cel. Mol. Bioeng. 2012, 5, 363-374. (Impact Factor 2.535)
The 3D-structural evaluation and binding of AIFM2 to DNA: An insilico study. Ramasree, D.; Satyaprakash, A.S.V.; Bhargavi, K.; Vasavi, M.; Uma, V. J. Pharmacy Research. 2012, 5, 3099. (Impact Factor 2.36)
Novel inhibitors targeting cell signaling receptor – cyclin D2 by virtual screening.Sarita, R. P.; Kiran, K. M.; Vasavi, M.; Uma, V. J. Pharmacy Research. 2012, 5, 572. (Impact Factor 2.36)
Angiogenesis: an insilico approach to angiogenic phenotype.Navaneetha, N.; Kiran, K. M.; Vasavi, M.; Bhargavi, K.; Sarita, R. P.; Ramasree, D.; Uma, V. J. Pharmacy Research. 2012, 5, 583. (Impact Factor 2.36)
Study of interactions between Mycobacterium tuberculosis proteins - Sig Kandanti - Sig K.Vasavi, M.; Bargavi, G.; Bhargavi, K.; Ramasree, D.; Uma, V. J. Mol. Model. 2011, 17, 1109. (Impact Factor 1.86)
Identification of novel selective antagonists for cyclin C by Homology modeling and virtual screening.Sarita, R. P.; Vasavi, M.; Uma, V. Int. J. Biol. Macromol. 2011, 48,292. (Impact Factor 3.09)
Homology Modeling and Docking Studies of Human Bcl-2L10 protein.Bhargavi, K.; Kalyan, C. P.; Ramasree, D.; Vasavi, M.; Murthy, D. K.;Uma, V.J.Biomol.Struct.Dyn. 2010, 28, 379. (Impact Factor 2.98.
Selective Inhibition of Proteins Regulating CDK / Cyclin Complexes: Strategy Against Cancer – A Review.Sarita, R. P.; Ramasree, D.; Bhargavi, K.; Vasavi, M.; Uma V.J. Recept. Signal. Transduct. Res. 2010, 30, 206. (Impact Factor 1.61)
Tricyclic Pthalimide Analogues as Novel Inhibitors of HIV-1 Integrase – A QSAR Study.Vasavi, M.;Kalyan, C. P.; Ramasree, D.; Sarita, R.; Uma, V. Bioinformatics Trends. 2007, 2, 61. (Impact Factor: Not available)
Multi drug resistant protein of Mycobacterium tuberculosis 3D Homology model. Generated and deposited in Protein Data Bank with PDB ID - 2IQ4. Vasavi, M.;Kalyan, C. P.; Ramakrishna, A.; Uma, V. (Oct - 2006). (Impact Factor: Not available).
- b. Procedings : 4
- Targeted therapy for cancer: An In silico approach, Aruna Airva, Upender Bowroju, Vasavi Malkhed &Navaneetha Nambigari, Second National Conference on Recent advances in applied nano materials, at Department of Physics, University College of Science, Saifabad, Osmania University, Hyderabad, February 16-17, 2018, International journal of research culture society, 2018, 47-52. (Impact factor 3.449)
- Small molecule identiﬁcation against novel MDRA protein of Mycobacterium tuberculosis.Kiran, K. M.; Vasavi, M.; Venkataramana R. C.;Uma, V.; J. Biomol. Struct. Dyn. 2013, 31, 1, 118. (Impact factor 2.98)
- Design of new leads as novel therapeutics for Tuberculosis - A computational approach.Uma, V.; Vasavi, M. 3rd World Congress on Biotechnology 2012, organized by Omics group, at HICC, Hyderabad, India on 13-15 September, 2012. J. BiotechnolBiomater 2012, 2, 6, 155. (Impact Factor: Not available)
- Design and synthesis of potent Cyclin C inhibitors.Sarita, R. P.; Kiran, K. M.; Bhargavi K.; Vasavi, M.; Uma, V. J. of Bioavailability and Bioequivalence. 2012, 4, 43. (Impact Factor 2.00)

Faculty Development Programms

Orientation Course : 2
Refresher Course : 2

Research Projects

1.UGC-BSR Start – Up Grant

Fellowships/Scholorships/Awards/Rewards

Young Scientist Award - 2010 in Chemistry & Allied Sciencesby Dr. K.V. Rao Scientific Society, Hyderabad, India.
Best poster prize for “Potent target for cancer therapy” in 4th Indo US Lecture series on Discrete Mathematical Chemistry (6-9th January 2009).

No.of Students Awarded Ph.D

Member of Professional Bodies

Indian Science Congress Association (L33317)

Extension Co-Curricular Work

I/C NCC Officer, University College of Science, Saifabad, Hyderabad – 500004

University College of Science, Saifabad, Osmania University,Hyderabad-500004,INDIA
Phone: + 91-040-23393530; 23375395; 23306136, Email: oupgcss@gmail.com